Vanotsvagurudza vakawana kuti iyo yekutanga metabolite ye thc inoramba ichivakirwa pane data kubva kune yedata kubva pamarazi. Dhata nyowani yekutsvagisa inoratidza kuti iyo huru thc metabolite lingering muUrine uye ropa inogona kuramba ichishanda uye seinoshanda seiyo thc, kana zvisingaite zvakadaro. Uku kutsvaga kutsva kwacho kunosimudza mibvunzo yakawanda kupfuura iyo inopindura. Maererano neicho chidzidzo chazvino chakaburitswa muzvinyorwa zvePharmacology uye psychoactive metabolite yeTC, 11-hydroxy-thc), ine yakaenzana kana yakakura psychoactive potency pane thc (delta-9 thc).
Chidzidzo ichi, titivedzo "mubatanidzwa wegumi--hydroxy-delta-9-thc (11-oh-thc) hama-9-thc," inoratidza kuti Thc metabolites chengetedza basa. Izvo zvinozivikanwa kuti thc inoputsa uye inogadzira mitsva inonakidza inonakidza kana ichitsvaga iyo Drarboxylate uye zviito mumuviri wemunhu. "Muchidzidzo ichi, takatema kuti primary metabolite of thc, kuratidzwa kwakaenzana kana kuenzanisa muzvinhu zvekutonga "Idzi data inopa zvakakosha zvevanonzwisisika kuita
Tsvagurudzo iyi yakaitwa nechikwata ichibva kuSaskatchewan, Canada, kusanganisira Ayat Zagzoog, Kenzie Halter, Joshua Cline, Alexis Wilcox, Anna-Maria Smollyakova, naRobert B. Labert B. Laprairie. Mukuedzwa, vaongorori vakapfeka makonzo evarume vane 11-hydroxy-thc uye cherechedzo uye vakadzidza miganho yeiyo thc metabolite tichienzanisa nemubereki, Delta-9 thc.
Vaongorori vanozviti:
Nekudaro, iyo chidzidzo inoratidza kuti thc metabolite 11-oh-thc inogona kutamba chikamu chakakosha mukuita zvinhu zvisina kujairika zve cannabis. Kunzwisisa chiitiko chayo kana kupihwa zvakananga kuchabatsira kutsanangura mhuka yemangwana uye zvidzidzo zvevanhu. Chirevo chinotaura kuti 11-o-thc ndeimwe yemaviri metabolites yakaumbwa mushure meCannabis play, imwe kuve yegumi nenomwe-yezvinhu-thc, iyo isiri psychoactive asi inogona kuramba iri muropa kana kurira kwenguva yakareba.
Maererano neUS nzvimbo dzekutonga kwechirwere uye kudzivirira (CDC), nguva yekutanga,
Chirevo chinonongedzera kuti kunyangwe vachiputa cannabis vanowanzogadzira nekukurumidza kupfuura kupedza canbis edibles, huwandu hwa11-oh-thc hunogadzirwa kuburikidza nekumisikidza kuputa cannabis maruva. Chirevo chinopa kuti ichi chimwe chikonzero nei chikafu chisina kuitwa chichiitwa chinogona kuve chichiwedzera chakawanda uye chinokonzeresa kuvhiringidzika kwevasina kugadzirira.
Thc metabolites uye zvinodhaka bvunzo
Uchapupu hunoratidza kuti cannabis dzinobata vashandisi zvakasiyana zvichienderana nenzira yekutonga. A ongororo 2021 yakaburitswa muzvinyorwa zvechigarire yakaratidza kuti zvinokonzerwa nekuparadza cannabis ecnabis yakakura kupfuura iyo yekuputa cannabis nekuda kweiyo metabolism ye11-oh-thc.
"Iyo yekubvarura yeiyo thc kuburikidza neVaporization ndeye 10% kusvika ku35%," vaongorori vakanyora. "Pashure pokunyora, thc inobviswa chiropa, apo vazhinji venyama kana metabilises yeTC chete, neiyo metabolilipity yeruzhinji, Plasma hafu-hupenyu hweTC mune dzimwe nguva vashandisi ndeye 1 kusvika pamazuva matatu, nepo vashandisi vasiri vaseri, zvinogona kunge zvishanu pamazuva mashanu kusvika gumi nematanhatu. "
Zvidzidzo zvinoratidza kuti nguva yakareba mushure mekunge psychoactive mhedzisiro yeCannabis yakapera, Izvi zvinokatyamadza nzira dzakajairika dzekuyedza kuti vatyairi nevatambi vanokanganiswa nekuda kweCannabis kushandiswa. Semuenzaniso, vatsvagiri veAustralia vanga vachizoedza kuona nguva iyo nguva iyo cannabis inogona kukanganisa kutyaira kuita. Mune imwe nguva, Thomas R. Arill, Danielle McCartney, uye Iain S. McGregor kubva kuLamboror Stanhoctive kuYunivhesiti yeSydney akafunda kukanganiswa kweCannabis pakurwara kwekutyaira. Chikwata chakatsiga kuti cannabis anokanganisa kugona kutyaira kwemaawa akati wandei mushure mekuputa fodya, asi izvi zvinopera pamberi peTHC yeTHC metabolites
"Varwere vachishandisa zvigadzirwa zveTC-vane mari vanofanira kudzivisa kutyaira uye kumwe kuchengeteka mabasa (semuenzaniso, panguva yekutanga yekurapa nguva uye kwemaawa akati wandei mushure mechikamu chimwe nechimwe," vanyori vakanyora. "Kunyangwe kana varwere vasinganzwisisike, vanogona kunge vachiri kuedza zvakanaka
Tsvagurudzo itsva iyi ye11-oh-thc inoratidza kuti zvimwe zvidzidzo zvinodikanwa kunyatsonzwisisa kuti sei thc metabolites inokanganisa muviri wemunhu. Chete kuburikidza nekuenderera mberi kwekuedza kunogona kutiluse zvizere zvakavanzika zveaya akasiyana makomputa.
Kutumira Nguva: Mar-21-2025